Chronic hand eczema (CHE) affects nearly 10% of U.S. adults, presenting significant challenges in management due to occupational exposures and a lack of effective treatment options. Recent insights from the CHECK observational study highlight the long-term burden of this condition, which often leads to prolonged flares that disrupt daily activities and impact mental health. In an interview with Pharmacy Times, Shannon Schneider, PhD, vice president of North America medical affairs at LEO Pharma, emphasized the role of pharmacists in bridging care gaps for patients suffering from CHE.
Schneider noted that while CHE is prevalent, effective treatment remains elusive. “Chronic hand eczema is eczema that occurs for greater than three months or relapses two or more times per year. It’s highly heterogeneous in its presentation,” she explained. The absence of an ICD-10 code for CHE has complicated its recognition in clinical settings. Until recently, the reliance on potent topical corticosteroids has been prevalent, despite these medications being unsuitable for long-term use.
Occupational Factors and Treatment Challenges
The CHECK study revealed that CHE prevalence is particularly high among younger adults, males, and those employed in certain sectors. Schneider indicated that individuals in occupations requiring frequent hand washing or exposure to irritants, such as healthcare or manufacturing, are especially at risk. “Pharmacists who understand their patients’ work environments can be instrumental in identifying those at risk for chronic hand eczema,” she stated.
Many patients reported experiencing flares lasting over three months, which complicates treatment planning. Schneider highlighted the difficulties posed by constant exposure to irritants in daily life, making it challenging to manage symptoms effectively. “For many patients, this has led to years of struggling to control their symptoms, with some needing to change jobs or modify their daily activities,” she added.
Psychosocial Impact and Pharmacists’ Role
The CHECK study also indicated a significant psychosocial burden associated with CHE. Approximately 70% of individuals with severe chronic hand eczema struggle with daily tasks, which can severely impact their quality of life. This burden extends to work productivity, with many patients needing to alter job responsibilities due to their condition.
Pharmacists play a crucial role in addressing these issues. Schneider pointed out that they can help recognize persistent or moderate to severe symptoms and facilitate timely referrals to dermatologists. “Patients may not be aware that new treatments are available. Pharmacists can connect them to appropriate long-term care,” she said.
Emerging therapies, including a new non-steroidal topical treatment, offer hope for patients seeking effective management options. Schneider emphasized the importance of patient education about these therapies, as many may still rely on traditional corticosteroids due to a lack of awareness.
As the healthcare landscape evolves, the need for awareness and proactive management of chronic hand eczema becomes increasingly critical. Pharmacists, equipped with knowledge about occupational risks and new treatment modalities, stand poised to make a significant impact on the lives of those affected by this challenging condition.
